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MOTS-c
MOTS-c is documented for controlled research models and literature-based evaluation only.
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MOTS-c is a 16-amino-acid mitochondrial-derived peptide supplied as a lyophilized research reagent. Manufactured for controlled laboratory use.
Research contexts include mitochondrial signaling, AMPK activation, insulin sensitivity modeling, and metabolic-flexibility studies.
Research Use Only. This product is intended exclusively for laboratory research and is not approved for human or veterinary use.
MOTS-c: investigational profile.
Research Mechanism
A 16-residue mitochondrial-derived peptide encoded within the 12S rRNA locus, investigated for AMPK activation, insulin sensitivity, and skeletal-muscle exercise metabolism. Frequently discussed alongside SS-31 when mitochondrial function is the endpoint.
Investigational Profile
First described by the Cohen laboratory in 2015 and now embedded in the mitochondrial-derived-peptide and exercise-metabolism literature.
Research Study Window
Metabolic-flexibility and AMPK-pathway endpoints are typically observed across four- to eight-week laboratory protocols.
Pairs With
AOD-9604
Ingredients, disclosed.
Every compound and formulation strength documented without proprietary blends.
Composition, documented.
- Molecular Formula
- C101H152N28O22S2
- Molar Mass
- 2174.6 g/mol
- Amino Acid Sequence
- H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH
- Synonyms
- Mitochondrial Open Reading Frame of the 12S rRNA-c, MOTS-c peptide
- Solubility
- Water-soluble
- Organoleptic Profile
- White to off-white powder
- Composition
- Lyophilized powder


